Lead Contamination in Driver's Blood and Its Effects on Erythrocytes, Leukocytes, and Platelets as A Biomarker

Authors

  • Pra Dian Mariadi Universitas Katolik Musi Charitas
  • Agnes Felicia Lubis Universitas Katolik Musi Charitas
  • Lidwina Septie Ch Universitas Katolik Musi Charitas

DOI:

https://doi.org/10.31851/sainmatika.v20i2.13010

Keywords:

Blood, Erythrocytes, Lead , Leukocytes , Platelet

Abstract

Lead as a component of air pollution has broad toxic effects and can be detrimental to humans, such as causing abnormalities in kidney function, digestive tract, nervous system, and hematopoietic disorders. Many people carry out their activities on the highway, one of which is an Angkot driver. Drivers who work on the road daily get direct exposure to air pollution, especially from lead (Pb). Therefore they are very vulnerable to the negative effects of lead (Pb). This study aimed to measure blood lead levels as a biomarker of lead contamination in a driving group in Palembang City. The subjects were drivers who had been working for more than 20 years (average 28 years) and the average age was 58 years. Testing blood lead levels using the APHA method and examining erythrocytes leukocytes and platelets using the impedance method and correlation test using the Spearman test. Based on the results of this study, there is a relationship between blood lead levels and erythrocyte (significance: 0.0019) and leukocyte (significance: 0.002) values, but there is no relationship between blood lead levels and platelet values (significance: 0.4), while blood lead levels in drivers are still within the threshold limit (average: 14.9804 µg/L).

References

Basil, Debra Z, Nancy M Ridgway, and Michael D Basil. 2008. “Guilt and Giving : A Process Model of Empathy and Efficacy.” Psychology & Marketing 25 (1)(January): 1–24.

Betz, C. L., Sowden, L. A. (2009) Handbook of Pediatric Nursing 5th Edition, Jakarta: Medical Book Publishers EGC.

Barsova, Natalia et al. 2018. “The Effect of Humic Substances on Cu Migration in the Soil Profile.” Chemistry and Ecology 0(0): 1–16. https://doi.org/10.1080/02757540.2018.1540613 .

Brücker, Herbert, Andreas Hauptmann, Elke J Jahn, and Richard Upward. 2014. “Migration and Imperfect Labor Markets : Theory and Cross-Country Evidence from Denmark, Germany and the UK." European Economic Review 66: 205–25. http://dx.doi.org/10.1016/j.euroecorev.2013.11.007.

Brucker, Natália et al. 2013. “Science of the Total Environment Biomarkers of Occupational Exposure to Air Pollution, in Fl Ammation and Oxidative Damage in Taxi Drivers." Science of the Total Environment, The 463–464: 884–93. http://dx.doi.org/10.1016/j.scitotenv.2013.06.098.

Cut Juliana, Nurjazuli, Suhartono. 2017. “Hubungan Kadar Timbal Dalam Darah Dengan.” HIGINE Vol 3 No 3: 161–68.

Dharma Koosgiarto, Abdul Hakim. 2015. “Pengaruh Kandungan Timbal Dalam Darah Terhadap Jumlah Eritrosit Pada Pekerja SPBU Di Wilayah Banyumas.” MEDISAINS 13(3): 48–57.

E V Kiyaeva, S V Notova. 2019. “Influence of Cadmium on Blood and Hair Trace Elements and Biochemical Markers Influence of Cadmium on Blood and Hair Trace Elements and Biochemical Markers.” Earth and Environmental Science Paper.

Farmand, Farbod, Ashkan Ehdaie, Christian K Roberts, and Ram K Sindhu. 2005. "Lead-Induced Dysregulation of Superoxide Dismutases, Catalase, Glutathione Peroxidase, and Guanylate Cyclase." 98: 33–39.

Fibrianti, R. Azizah. 2015. “Karakteristik, Kadar Timbal (Pb) Dalam Darah, Dan Hipertensi Pekerja Home Industry Aki Bekas Di Desa Talun Kecamatan Sukodadi Kabupaten Lamongan.” Jurnal Kesehatan Lingkungan 8: 92–102.

Fitriana, Alvionita Nur. 2015. “Forensic Toxicology.” J MAJORITY Vol 4 No 4 4: 1–9

Flora, Gagan, Deepesh Gupta, and Archana Tiwari. 2012. “Toxicity of Lead : A Review with Recent Updates.” Interdisciplinary Toxicology 5(2): 47–58.

Gusnita, Dessy. 2012. “Pencemaran Logam Berat Timbal (Pb) Di Udara Dan Upaya Penghapusan Bensin Bertimbal.” Penelitian Bidang Komposisi Atmosfer, LAPAN: 95–101.

Hao, Annec et al. 2014. “Rarefaction and Extrapolation with Hill Numbers : A Framework for Sampling and Estimation in Species Diversity Studies.” 84(1): 45–67.

Jemani, Muhammad Rizki Kurniawan. 2019. “ANALISA QUALITY CONTROL HEMATOLOGI DI LABORATORIUM RUMAH SAKIT AN-NISA TANGERANG ANALYSIS OF HEMATOLOGY QUALITY CONTROL IN AN-NISA TANGERANG HOSPITAL.” 1: 80–85.

Kumar, Amit, Amit Kumar, and Ashish K Chaturvedi. 2020. "Lead Toxicity : Health Hazards, Influence on Food Chain, and Sustainable Remediation Approaches." Environmental Research and Public Health: 1–33.

Lailiyana, Zuchrah Hasan, JM.Metha, and Okta Vitriani. 2018. “HUBUNGAN PAPARAN TIMBAL AIR SUNGAI SIAK TERHADAP KADAR HEMOGLOBIN REMAJA PUTERI DI PEMUKINAN PINGGIRAN SUNGAI SIAK KOTA PEKANBARU TAHUN 2016.”

Lily Gunawan, Onny Setiani, Suhartono. 2013. “Hubungan Kadar Timah Hitam Dalam Darah Dengan Jumlah Lekosit , Trombosit , Dan Aktifitas Superoxide Dismutase ( SOD ) Pada Pekerja Timah Hitam Di Kabupaten Tegal The Association Beetwen Blood Lead Level with the Amount of Lekosit , Trombosit , and Superox.” Jurnal Kesehatan Lingkungan Indonesia 12(2): 106–10.

Lorenzo, Marisa Corfiati. 2006. “Evaluation of Peripheral Blood Neutrophil Leucocytes in Lead-Exposed Workers.” : 491–98.

Mariadi, Kurniawan. 2018. “Lead and Cadmium Mobilization From ANAS MOSCHA AND CAIRINA MOSCHATA TISSUE USING PINEAPPLE EXTRACT AS CHELATING AGENTS.” POLLUTION RESEARCH VOL 32 (2): 330–33.

Mariadi, Pra Dian et al. 2021. “Penggunaan Darah Sebagai Biomarker Paparan Logam Cadmium Masyarakat Pesisir Sungai Musi ( Efek Terhadap Eritrosit Dan Leukosit ).” 18(2): 208–14.

Mariadi, Pra Dian, and Rosnita Sebayang. 2017. “Science & Technology Indonesia Using Citric Acid from Pineapple Extract ( Ananas Comosus ) as Chelating Agent.” Science & Technology Inodnesia 2: 89–91.

Mezynska, Magdalena, and Malgorzata M Brzóska. 2017. “Environmental Exposure to Cadmium — a Risk for Health of the General Population in Industrialized Countries and Preventive Strategies.” (Cd).

Permenkes RI No 43 TAHUN. 2013. JAKARTA. menkes.go.id.

Popescu, C G. 2011. “RELATION BETWEEN VEHICLE TRAFFIC AND HEAVY.” Environmental Physics 63(2): 471–82.

Prasetya, Hieronymus Rayi. 2021. “HUBUNGAN TIMBAL DARAH TERHADAP KELAINAN.” Meditory 9(6): 44–53.

Putri, Dini Arista, Amrina Rosyada, and Elvi Sunarsih. 2018. “ANALISIS KADAR TIMBAL ( Pb ) DALAM RAMBUT DAN HIPERTENSI PADA PEKERJA PT . BUKIT ASAM UNIT DERMAGA KERTAPATI ANALYSIS OF LEAD LEVEL IN HAIR AND HYPERTENSION OF WORKER IN BUKIT ASAM DOCK UNIT KERTAPATI.” 9(1): 21–27.

Rosita, Betti. 2018. “HUBUNGAN TOKSISITAS TIMBAL ( Pb ) DALAM DARAH DENGAN HEMOGLOBIN PEKERJA PENGECATAN MOTOR PEKANBARU.” 1(1).

Setianto, Heri, and Husni Fahritsani. 2019. “Faktor Determinan Yang Berpengaruh Pencemaran Sungai Musi Kota Palembang.” 20(2): 186–98.

Soleman, Sani Rachman, Shafira Alifiana Andini, and Linda Rosita. 2020. “Lead Exposure Effect on Peripheral Blood Parameters among People around Bus Terminal in Yogyakarta.” (February): 11–16.

Tyas, Delly ANggun Cahyaning. 2021. “JUMLAH, HUBUNGAN KADAR Pb DALAM DARAH DENGAN KOTA, TROMBOSIT PADA PENDUDUK PESISIR SUNGAI MUSI DI PALEMBANG.”

Zahrotun hasanah, Suhartono, Nikie Astorina. 2018. “Pengaruh Kadar Timbal Dalam Darah Terhadap Jumlah Trombosit Pada Ibu Hamil Di Daerah Pantai Kabupatern Brebes.” Jurnal Kesehatan Masyarakat (e-Journal) 6: 393–98.

Zhang Yingfei, Zheng Feei Ma. 2020. "Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China : A Cross-Sectional Study.”

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Published

2023-11-25